Fluoroquinolones as potential photochemotherapeutic agents: covalent addition to guanosine monophosphate.
نویسندگان
چکیده
The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom at position 8 attacks guanosine monophosphate (k(r) > 10(9) M(-1)s(-1)) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 16 شماره
صفحات -
تاریخ انتشار 2010